Comorbidities in the Elderly Living with HIV/Aids
DOI:
https://doi.org/10.18316/sdh.v8i1.6110Keywords:
Health Services for the Aged, HIV Infections, Opportunistic Infections, Noncommunicable DiseasesAbstract
Objective: To identify the clinical and epidemiological profile of older people living with HIV/Aids.
Materials and methods: This was an observational, documentary, cross-sectional, prospective, descriptive and analytical study, conducted from clinical records of the Specialized Attention Service.
Results: The study included 64 elderly, of which 53% (34) were men and 47% (30) were women, 81% (52) had completed or less than complete elementary school, 67,18% (43) had TCD4 lymphocytes ? 350 cells/mm³, 81% (52) had viral load ? 40 copies/mL, 97% (62) were infected by heterosexual relationship and 84,5% (54) had at least one comorbidity. Cachexia (48%), anemia (35%), smoking (31,5%) and systemic arterial hypertension (18,5%) were the most common noncommunicable diseases. Oral candidiasis (55,55%) was the opportunistic diseases with higher incidence in the elderly participants of the study.
Conclusion: The presence of comorbidities and opportunistic infections should be investigated among elderly with HIV to ensure support and better care for these individuals.
References
Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Boletim epidemiológico HIV Aids 2018. Brasília, 2018a.
Boender TS, Smit C, Sighem AV, Bezemer D, Ester CJ, Zaheri S, et al.
AIDS Therapy Evaluation in the Netherlands (ATHENA) national observational HIV cohort: cohort profile. BMJ Open 2018;8:e022516.
Affeldt ÂB, Silveira MFD, Barcelos RS. Perfil de pessoas idosas vivendo com HIV/aids em Pelotas, sul do Brasil, 1998 a 2013. Epidemiol Serv Saúde 2015;24:79-86.
Allavena C, Hanf M, Rey D, Duvivier C, BaniSadr F, Poizot-Martin I, et al. Antiretroviral exposure and comorbidities in an aging HIV-infected population: The challenge of geriatric patients. PloS one; 2018;13(9):e0203895.
Legarth RA, Ahlström MG, Kronborg G, Larsen CS, Pedersen G, Mohey R, et al. Long-Term Mortality in HIV-Infected Individuals 50 Years or Older: A Nationwide, Population-Based Cohort Study. J Acquir Immune Defic Syndr 2016;71(2):213–8.
Brasil. Ministério da Saúde. Departamento de Vigilância, Prevenção e Controle das Infecções Sexualmente Transmissíveis, do HIV/Aids e das Hepatites Virais. Protocolo Clínico e Diretrizes Terapêuticas para Manejo da Infecção pelo HIV em Adultos. Brasília, 2018b.
Fontela C, Castilla J, Juanbeltz R, Martínez-Baz I, Rivero M, O’Leary A. Comorbidities and cardiovascular risk factors in an aged cohort of HIV-infected patients on antiretroviral treatment in a Spanish hospital in 2016. Postgraduate Medicine 2018;130(3):317-324.
Mpondo BCT. HIV infection in the elderly: Arising challenges. J Aging Res 2016;2016.
Laroque MF, Affeldt ÂB, Cardoso DH, de Souza GL, Glória Santana M, Lange C. Sexualidade do idoso: comportamento para a prevenção de DST/AIDS. Rev Gaúcha Enferm 2011;32(4):774.
Mack KA, Ory MG. AIDS and older Americans at the end of the twentieth century. J Acquir Immune Defic Syndr 2016;33(supplement 2):S68–S75, 2016.
Mensforth S, Goodall L, Bodasing N, Coultas J. Late diagnosis among our ageing HIV population: a cohort study. J Int AIDS Soc 2014;17:192-6.
Fernandes MA, Pires FMDJS, Bezerra MM, Alencar NES, Lima FFF, Sousa Ibiapina AR. Doenças sexualmente transmissíveis: sentimentos das presidiárias. Rev Int Interdisciplinar 2015;8(3):162-168.
Maciel RA, Klück HM, Durand M, Sprinz E. Comorbidity is more Common and Occurs Earlier in Persons Living with HIV than in HIV-uninfected matched controls, aged 50 years and older: A cross-sectional Study. Int J Infect Dis 2018;70:30-35.
Group ISS. Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection. Insight Start Study Group. N Engl J Med 2015;373(9):795-807.
Guaraldi G, Malagoli A, Calcagno A, Mussi C, Celesia BM, Carli F, et al. The increasing burden and complexity of multi-morbidity and polypharmacy in geriatric HIV patients: a cross sectional study of people aged 65–74 years and more than 75 years. BMC Geriatr 2018;18(1):99.
Guaraldi G, Orlando G, Zona S, Menozzi M, Carli F, Garlassi E, et al. Premature age-related comorbidities among HIV-infected persons compared with the general population. Clin Infect Dis 2011;53(11):1120-6.
Bekele T, Rueda S, Gardner S, Raboud J, Smieja M, Kennedy R, et al. Trends and Correlates of Cigarette Smoking and Its Impacts on Health-Related Quality of LifeAmong People Living with HIV: Findings from the Ontario HIV Treatment Network Cohort Study, 2008-2014. AIDS Patient Care STDs 2017;31(2):49-59.
Williams EC, Hahn JA, Saitz R, Bryant K, Lira MC, Samet JH. Alcohol use and human immunodeficiency virus (HIV) infection: current knowledge, implications, and future directions. Alcohol Clin Exp Res 2016;40(10):2056-72.
Wang T, Fu H, Kaminga AC, Li Z, Guo G, Chen L, et al. Prevalence of depression or depressive symptoms among people living with HIV/AIDS in China: a systematic review and meta-analysis. BMC psychiatry 2018;18(1):160.
Coelho L, Cardoso SW, Amancio RT, Moreira RI, Campos DP, Veloso VG. Trends in AIDS-defining opportunistic illnesses incidence over 25 years in Rio de Janeiro, Brazil. PLoS ONE 2014;9(6):e98666.
Low A, Gavriilidis G, Larke N, B-Lajoie MR, Drouin O, Stover J, et al. Incidence of opportunistic infections and the impact of antiretroviral therapy among HIV-infected adults in low- and middle-income countries: a systematic review and meta-analysis. Clin Infect Dis 2016;62(12):1595–603.
Reniers G, Slaymaker E, Nakiyingi-Miiro J, Nyamukapa C, Crampin AC, Herbst K, et al. Mortality trends in the era of antiretroviral therapy: evidence from the network for Analysing longitudinal population based HIV/AIDS data on Africa (ALPHA). AIDS 2014;28(4):533–42.
Weldegebreal T, Ahmed I, Muhiye A, Belete S, Bekele A, Kaba M. Magnitude of opportunistic diseases and their predictors among adult people living with HIV enrolled in care: national level cross sectional study, Ethiopia. BMC public health 2018;18(1):820.
Downloads
Published
Issue
Section
License
Authors who submit their manuscripts to be published in this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under the Creative Commons Attribution License that allows the sharing of work and recognition of its initial publication in this journal.
- By virtue of the articles appearing in this open access journal, articles are free to use, with proper attribution, in educational and non-commercia.