Efeitos do Exercício Físico na Resposta da Interleucina-6 Durante o Tratamento da Síndrome Metabólica

Autores/as

  • Irineu Otavio Marchiori Callegari Departamento de Educação Física, Instituto de Biociências da Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP), Rio Claro, SP – Brasil.
  • Alexandre Gabarra Oliveira Departamento de Educação Física, Instituto de Biociências da Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP), Rio Claro, SP – Brasil.

DOI:

https://doi.org/10.18316/sdh.v10i3.9029

Palabras clave:

Inflamação, Exercício Físico, Obesidade, Doenças Crônicas Não-transmissíveis, Saúde

Resumen

Introdução: Os componentes que caracterizam a síndrome metabólica (SM) envolvem complicações decorrentes do estado infl amatório subclínico, principalmente quando combinado ao sedentarismo e excesso na ingestão de nutrientes. Entretanto, aumento no nível de atividade física pode prevenir a incidência de SM. Objetivo: Compreender a infl uência do exercício físico no tratamento da SM associado aos níveis de interleucina-6 (IL-6). Materiais e Métodos: A revisão narrativa foi construída com 36 referencias obtidas pela interação das palavras-chave síndrome metabólica, IL-6, atividade física e exercício físico na plataforma PUBMED, considerando apenas estudos em inglês realizados com seres humanos. Resultados e Discussão: Os níveis plasmáticos de IL-6 diminuem após intervenções que propuseram aumento signifi cativo do nível de atividade física, principalmente através de exercício aeróbio de moderada intensidade combinado com o treinamento resistido. Além disso, o exercício físico promove a redução da infl amação, adiposidade central, triglicérides, pressão arterial sistólica e lipoproteína de baixa densidade, além de aumentar os níveis de lipoproteína de alta intensidade, o que colabora com o controle da SM. Considerações Finais: A liberação local de IL-6 pelo músculo esquelético contribui com a redução da infl amação subclínica da SM, sobretudo nas intervenções que aliaram o exercício junto a estratégias de controle nutricional.

 

Biografía del autor/a

Alexandre Gabarra Oliveira, Departamento de Educação Física, Instituto de Biociências da Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP), Rio Claro, SP – Brasil.

Fisiologia do Esforço e Endocrinologia do Exercício

Citas

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Publicado

2022-10-11

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Artigos de Revisão